Name: Non-Invasive Monitoring of Transdermal Drug Delivery (en Inglés)
Price: 530738.00 COP
Availability: InStock
Author: Pasquale Arpaia; Umberto Cesaro; Nicola Moccaldi; Isabella Sannino
ISBN: 9780367765989

portada Non-Invasive Monitoring of Transdermal Drug Delivery (en Inglés)

Formato

Libro Físico

Editorial

Crc Press

Autor

Pasquale Arpaia; Umberto Cesaro; Nicola Moccaldi; Isabella Sannino

Idioma

Inglés

N° páginas

174

Encuadernación

Tapa Dura

ISBN13

9780367765989

N° edición

Non-Invasive Monitoring of Transdermal Drug Delivery (en Inglés)

Pasquale Arpaia; Umberto Cesaro; Nicola Moccaldi; Isabella Sannino (Autor) · Crc Press · Tapa Dura

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Reseña del libro "Non-Invasive Monitoring of Transdermal Drug Delivery (en Inglés)"

The book presents an innovative technology based on injection of a very weak current to trace the quantity of a drug carried immediately after the administration. The book makes the reader familiar with the technology, from the conception through the design of the instrument, up to the preliminary clinical applications. In the first chapter, the method of transdermal drug delivery and the use of impedance spectroscopy in the dermatological field are presented. The second chapter describes a screening measurement campaign aimed at proving the feasibility of the assessment method and identifying the bandwidth of interest. The prototyping, validation and characterization of an instrument to measure the amount of drug delivered (DUSM: Drug Under Skin Meter) are presented in chapter three. In the fourth chapter three experimental campaigns, based on the electrical analysis of the biological tissue behavior due to the drug delivery, are reported: (i) laboratory emulation on eggplants, (ii) ex-vivo tests on pig ears, and finally (iii) in-vivo tests on human volunteers. In the fifth chapter a behavioral model, based on Finite Elements and Partial Differential Equation, of an impedance-based measurement system for assessing the drug released under the skin, during transdermal delivering, is proposed. The last chapter is dedicated to present a campaign in order to prove the suitability for insulin therapy applications. This book is intended for biomedical engineers, biomedical engineering students, operators working in the field of biomedical instrumentation, biotechnologists, and technicians of transdermal vehiculation.