Name: Approach to the genetic study of epithelial ovarian cancer (en Inglés)
Price: 275900.00 COP
Availability: InStock
Author: García Aliaga, Ángeles
ISBN: 9786207426249

portada Approach to the genetic study of epithelial ovarian cancer (en Inglés)

Formato

Libro Físico

Autor

Ángeles García Aliaga

Editorial

Our Knowledge Publishing

Idioma

Inglés

N° páginas

Encuadernación

Tapa Blanda

Dimensiones

22.9 x 15.2 x 0.3 cm

Peso

0.09 kg.

ISBN13

9786207426249

Categorías

Ciencias matemáticas

Approach to the genetic study of epithelial ovarian cancer (en Inglés)

Ángeles García Aliaga (Autor) · Our Knowledge Publishing · Tapa Blanda

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Origen: Estados Unidos (Costos de importación incluídos en el precio)

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Reseña del libro "Approach to the genetic study of epithelial ovarian cancer (en Inglés)"

Ovarian cancer is the gynecological cancer with the highest mortality, with high-grade serous ovarian cancer accounting for 75% of this pathology, characterized by having an aggressive course and being diagnosed in advanced stages. One of the inclusion criteria according to the Spanish Society of Medical Oncology for high-risk hereditary breast and ovarian cancer syndrome (HOCCOS) is the diagnosis of non-mucinous high-grade epithelial ovarian cancer. SCMOH has an autosomal dominant inheritance pattern in cancer susceptibility genes. Historically, the risk of SCMOH has been mainly linked to germline mutations in BRCA1/2. However, it is now also associated with tumor suppressor genes involved in DNA repair. High-grade ovarian cancer is evidenced by being genetically unstable and approximately 50% of these tumors are deficient in DNA repair mechanisms by homologous recombination.